Hilltop Bio is pleased to announce the official launch of Strydaflex, a revolutionary product in equine joint health. Hilltop Bio produces the most technologically advanced, convenient and consistent room-temperature regenerative therapies available on the market today.
Strydaflex, Hilltop Bio’s new equine joint therapy
“Because joint issues are one of the most common problems plaguing equine athletes, we’ve devoted extensive R&D to formulating a joint therapy that not only reduces inflammation, but also helps repair damaged tissue,” stated Hilltop Bio CEO, Amanda Drobnis. “We’re excited to introduce Strydaflex for equine joints, a game changer for equine veterinarians and their patients. Strydaflex joins our existing line-up of room-temperature regenerative therapies that includes Regenaflex-RT for soft tissue injuries and Regenaflex-M for wounds and surgical implantation. As with our other products, Strydaflex is 100% natural and offers the unparalleled convenience of off-the-shelf stability for up to a year, whether that shelf is in your clinic or on your truck.”
Hilltop Bio has completed a pilot safety study on the original cold formulation and is currently conducting a follow up study for the lyophilized version. Initial data indicate that both versions appear to be well tolerated and have demonstrated positive outcomes in horses with clinical lameness.
Traditionally, corticosteroids have been the default treatment for joints because they are great anti-inflammatories. But a large body of evidence indicates that long-term and/or high volume use of corticosteroids can have a serious negative effect on cartilage cells, even to the point of cell death.
According to Dr. Dan Dreyfuss, “Most of the autologous derived products, whether you’re talking about an autologous conditioned serum, an autologous protein solution, PRP; all of those do a really good job of concentrating factors from the blood that you can administer intra-articularly. The problems are (a) you don’t know what exactly is in there that’s working, and (b) they’re also concentrating pro-inflammatory cytokines that you’re then putting in the joint. And that's not good for the joint.”
He summed up, “Being able to custom engineer these products for different uses is what, in my opinion, sets Hilltop apart from the rest of the crowd. And it's a really important distinction. Strydaflex has factors in it that are going to take an inflamed synovium, which is over producing proinflammatory cytokines, and quiet it down so that the Strydaflex, based on its characterization, is going to incite that synovium to become happier, healthier, and less inflamed. And in the process of doing that, the synovium will produce much better hyaluronic acid within the joint which will contribute to the overall health of the joint.”
Watch Dr. Dan Dreyfuss’s full explanation on joint health and Strydaflex
The evolution of orthobiologics available for treating equine patients
The regenerative therapy industry has seen rapid changes in the last two decades. Technological and scientific advancements have empowered veterinarians to provide better care for their patients. Drobnis commented, “Most veterinarians are familiar with using stem cell, PRP, IRAP, and ProStride options for soft tissue injuries. What we’re seeing in the scientific literature available today is that it’s not just the stem cells that fix these injuries, rather it’s the exosomes within those stem cells that have the proteins, growth factors, and cytokines as well as the cell-signaling power already available in the horse’s body. At Hilltop Bio, we’re focused on being the leader in the most technologically advanced regenerative therapy market. We’re concentrating the exosomes into our formulations to work naturally with the horse’s own immune system to up-regulate its healing power and fix itself with minimal scar tissue, reduced inflammation, minimal risk of infection and reduced re-injury rates. We’re also offering a more consistent product in terms of proteins and growth factors compared to other modalities available on the market today.”
Top veterinarians like US Show Jumping team vets, Dr. Tim Ober and Dr. Heather Sherman of Steele & Associates, have been using Hilltop products for a number of years. Dr. Ober stated, “We have been using Regenaflex to treat suspensory ligament and check ligament injuries for the past three years. We are seeing consistency in the healing response with good quality repair, and a much more consistent return to performance than with other regenerative approaches we have used.”
See Hilltop Bio’s recent advertorial on Regenaflex-RT and Regenaflex-M here.
Hilltop Bio is a veterinary biotech company developing innovative regenerative therapies focused on identifying key inflammatory diseases in horses and companion animals and providing targeted regenerative therapies to help reduce inflammation and normalize damaged tissue function. Hilltop Bio has developed a strong pipeline of innovative therapies across many therapeutic classes, alongside cGMP, cGTP manufacturing capabilities and a developing intellectual property portfolio. Hilltop Bio is dedicated to providing targeted therapies that help horses and companion animals regenerate damaged tissues, and that will assist in restoring them to their full athletic potential and long-term health. For more information, visit www.hilltopbio.com.
Then